The Alfredo A. Sadun Neuro-Ophthalmology Collection: A Professor of Ophthalmology and Neurological Surgery at the USC Keck School of Medicine, Dr. Sadun with a team of researchers at the Doheny Eye Institute pioneered research in optic nerve dysfunction in patients with Alzheimer's disease. Contains his "100 best lectures." Alfredo A. Sadun, MD, PhD, Flora L. Thornton Chair, Professor Ophthalmology & Neurological Surgery, Doheny Eye Institute, Keck School of Medicine at USC.
NOVEL: https://novel.utah.edu/
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| Title | Description | Type | ||
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| 1 |
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The 360 Degree Evaluation | Evaluation of medical residents by faculty, hospital staff, peers, and patients. | Text |
| 2 |
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A Neuro-Ophthalmologist's View of RGC Apoptosis and Neuroprotection | Slide presentation with several microscopic images demonstrating cell death, LHON, AIDS. Anatomy: Optic nerve; Retina; Retinal ganglion cells; Phosphopyruvate Hydratase; Reactive oxygen species. Disease/Diagnosis: Optic Atrophy, Hereditary, Leber; Acquired Immunodeficiency Syndrome; Glaucoma. Presen... | Text |
| 3 |
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Accreditation and the RRC | A slide presentation providing information on accreditation and the residency review committee (RRC). | Text |
| 4 |
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The Accreditation Council for Graduate Medical Education's (ACGME) The New Competences | Presented at the PAAA/AAO Symposium on Teaching Residents Ophthalmology in the 21st Century, in Buenos Aires, July 2007 | Text |
| 5 |
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Acute Retrobulbar Optical Neuropathy | PPT covering acute retrobulbar optic neuropathy, including ischemic, inflammatory, anterior ischemic optic neuropathy (AION) and non-arteritic anterior ischemic optic neuropathy (NAION); includes brainscan images for optic neuritis and multiple sclerosis; optic disk with LHON and PION. Anatomy: Opt... | Text |
| 6 |
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AIDS: Neuro-Ophthalmologic Manifestations | Discusses various neuro-opthalmological complications to which AIDS patients are prone, and results of experimental testing on rabbits using Pentoxifylline. Anatomy: Optic nerve; Axons; Optic disk; Astrocytes; Macrophages. Pathology: Slides showing astrocytes, macrophages, cytokine staining. Disease... | Text |
| 7 |
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An Epidemic of Blindness in Cuba: Lessons on Nutrition and Mitochondria | Presented at Stanford in April 2007, recapping the 1990s expedition to Cuba to investigate causes of blindness epidemic. Anatomy: Optic nerve. Disease/Diagnosis: Optic nerve diseases; Alcoholic neuropathy. Treatment: Folate. Presenting Symptom: Ambliopia; Ataxia; Paresthesia; Hyporeflexia. | Text |
| 8 |
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Anatomy and Physiology of the Optic Nerve | Lecture covering the anatomy and physiology of the optic nerve. Covers the retina and anterior visual pathways. Several slides show microscopic images of optic nerve damage. Anatomy: Optic nerve; Retina; Retinal ganglion cells; Cytokines. Disease/Diagnosis: Glaucoma. | Text |
| 9 |
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Anatomy and Physiology of Vision: The Visual Pathways | Introduction to neuro-ophthalmology, covering the optic nerve, the afferent visual system (eye to brain), the pupil (Afferent-Efferent Reflex), and the efferent visual system (eye movements). Anatomy: Optic nerve; Optic disc; Retina; Retinal ganglion cells; Optic chiasm; Visual cortex. Disease/Diagn... | Text |
| 10 |
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Apoptosis in LHON: An ROS Explanation | A slide presentation describing apoptosis in LHON; includes several images of optic nerve and optic disk. Anatomy: Optic nerve; Optic disk; Retinal ganglion cells; Reactive oxygen species. Disease/Diagnosis: Optic Atrophy, Hereditary, Leber. | Text |
| 11 |
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Apoptosis of Retinal Ganglion Cells | Presented at a conference on neuroprotection at Sedona, Arizona, 2002; includes several microscopic images demonstrating cell death. Anatomy: Optic nerve; Retina; Retinal ganglion cells; Cytokines. Disease/Diagnosis: Glaucoma. | Text |
| 12 |
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Are IV Steroids and Anti-Platelet Agents Indicated in Every Case of GCA? | From a debate at a meeting in Canada in Sept. 2006, with Sadun taking the "pro" position. Disease/Diagnosis: Giant cell arteritis. Treatment: Methylprednisolone Hemisuccinate; Solumedrol; Prednisone; Aspirin. | Text |
| 13 |
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Atypical Optic Neuropathies | A discussion of atypical optic neuropathies. Anatomy: Optic nerve; Optic disc. Pathology: Slides showing LHON. Disease/Diagnosis: Optic neuropathy, Ischemic; Optic atrophy, Hereditary, Leber; Toxic optic neuropathy. Presenting Symptom: Optic neuritis; Eye hemorrhage; Retinal vasculitis; Dyschromatop... | Text |
| 14 |
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Beyond the Margulis Hypothesis: The Time Bomb Within Us | Presented at Harvard, 2005; includes several images of optic disc with LHON. Anatomy: Optic nerve; Optic disk; Retinal ganglion cells; Reactive oxygen species. Disease/Diagnosis: Optic Atrophy, Hereditary, Leber. Presenting Symptom: Dyschromatopsia; Scotoma. | Text |
| 15 |
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Beyond the Margulis Hypothesis: The Time Bomb Within Us | Presented at 36th Annual Doheny Days, 2005. Anatomy: Optic nerve; Retina; Retinal ganglion cells; Reactive oxygen species. Disease/Diagnosis: Optic Atrophy, Hereditary, Leber. | Text |
| 16 |
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Beyond Visual Acuity: New Measures in the Evaluation of Vision | Use of Amsler charts and 3-D computer imaging to evaluate visual acuity, sensitivity, and health. Disease/Diagnosis: Glaucoma; Age related macular degeneration. Presenting Symptom: Scotoma. | Text |
| 17 |
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Beyond Visual Acuity: New Measures in the Evaluation of Vision | Use of Amsler charts and 3-D computer imaging to evaluate visual acuity, sensitivity, and health. Disease/Diagnosis: Glaucoma; Age related macular degeneration. Presenting Symptom: Scotoma. | Text |
| 18 |
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Circadian Rhythms: How Much Retina Do We Need for a Good Night's Sleep? | Discusses importance of the health of the retinohypothalamic tract in the maintenance of circadian rhythm. Anatomy: Retina; Hypothalamus; Retinal ganglion cells; Pineal gland. Disease/Diagnosis: Retinal diseases; Sleep disorders, Circadian rhythm. | Text |
| 19 |
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The Clinical Spectrum of Amiodarone-Associated Optic Neuropathy | Sadun's response to a paper by L.N. Johnson, G.B. Kroheld, and E.R. Thomas at 2004 AAO meeting. Anatomy: Optic nerve. Disease/Diagnosis: Optic nerve diseases; Optic neuropathy, Ischemic | Text |
| 20 |
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Color Vision: Insights Into Our Origins and Some of Our Artists - From Darwin to Delacroix | Discussion of origins and physiology of color vision in different species, distinction between addition and subtraction of colors, and how painters get around the difference. Includes microscopic views of retinal cones. Anatomy: Retina; Rods (Retina); Cones (Retina). | Text |
| 21 |
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Compressive Optic Neuropathies Potpourri | An overview of compressive optic neuropathies, including symptoms, varieties, testing, and treatments; slide presentation includes several neuroimaging scans. Anatomy: Optic nerve. Disease/Diagnosis: Compression of optic nerve. Treatment: Mifepristone | Text |
| 22 |
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Controversies - Anatomy and Treatment of Dyslexia | A slide presentation on dyslexia. | Text |
| 23 |
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Cortical Visual Phenomena (Anton's to Geschwind's) | Part 6 of a course taught at Stanford University. Anatomy: Visual cortex. Disease/Diagnosis: Aphasia; Blindness, Cortical; Hallucinations, Visual; Anton's Syndrome; Visual Agnosia; Palinopsia; Geschwind's Syndrome; Apraxia; Cortical paralysis of fixation syndrome; Alzheimer's Syndrome. | Text |
| 24 |
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Cuban Epidemic of Optic Neuropathy: Even Zealots Must Eat, or, Conversations with Castro | A team of neuro-opthalmologists visits Cuba in 1993 and 1994, and attempts to treat patients with vision disorders. Anatomy: Optic nerve; Structure of cribriform plate. Disease/Diagnosis: Optic nerve diseases; Blindness; Ambliopia; Alcoholic neuropathy. Treatment: Folate. Presenting Symptom: Ataxia;... | Text |
| 25 |
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Cuban Epidemic of Optic Neuropathy: Even Zealots Must Eat, or, Conversations with Castro | A team of neuro-opthalmologists visits Cuba in 1993 and 1994, and attempts to treat patients with vision disorders. Anatomy: Optic nerve. Disease/Diagnosis: Optic nerve diseases; Alcoholic neuropathy. Treatment: Folate. Presenting Symptom: Blindness; Ambliopia; Ataxia; Paresthesia; Hyporeflexia. | Text |