1994 Alfred P. Sloan Winners Annoucement

Scientists today are learning exactly how disease-causing genes trip up the body's healthy functioning, thanks to a feat of molecular wizardry that is becoming as essential to researchers worldwide as a hammer is to a carpenter. Known as gene targeting, this revolutionary technique enables scientists to engineer mice with any gene defect imaginable, to create accurate models of cancer, high blood pressure, arteriosclerosis and a host of other diseases.