Description |
Scheme electron microscopy. A 11-15 m cell with a bilobed nucleus (1) moderate amount of organelles, mitochondria (2), Golgi area (3), many vesicles (5) and numerous specific eosinophilic granules (4). These granules contain a central electron-dense angular crystalloid core embedded in a finely granular matrix. The crystalloid consists of an alkaline protein (major basic protein or MBP); the matrix contains lysosomal hydrolases and lysophospholipase, myeloperoxidase, lactoferrin, eosinophilic cationic protein (ECP). Occasionally smaller light microscopic azurophilic granules might be present with a high content of acid phosphatase, arylsulfatase. |