Late band-form of neutrophilic granulocyte (peripheral blood, human)

Update item information
Title Late band-form of neutrophilic granulocyte (peripheral blood, human)
Creator Poels, Lambert G.
Contributor Lambert G. Poels, PhD, UMC St Radboud Nijmegen; Paul H. K. Jap, PhD, UMC St Radboud Nijmegen
Date 2007-12-01
Description Electron microscopy. Band forms (9-12 μm) are the earliest stages of the motile two-lobed granulocytes. The horseshoe shaped nucleus (3) is irregularly and indicates progressing lobulation. The neutrophil contains many granules of varying sizes and densities. On base of routine electron microscopy primary and secondary granules can be discerned. The primary, spherical to ellipsoid granules (1) are (lightmicroscopic) azurophilic granules, (diameter 0.4 μm) (arrows). They contain e.g. acid hydrolases as acid phosphatase, arylsulfatase, glucuronidase, but also myeloperoxidase as an antibacterial substance. The smaller, secondary or specific granules (2) are of varying forms (↓ dumb-bell form) and sizes, (diameter 0.2 μm up to length 0.8 μm). They contain substances like lysozyme, phagocytin to be secreted extracellularly involved in mobilization of inflammatory mediators and complement activation.
Subtype Image
Format image/jpeg
Collection Poja Histology Collection - Blood & Bone Marrow Subset
ARK ark:/87278/s6zs5zrg
Setname ehsl_heal
Date Created 2012-12-11
Date Modified 2012-12-11
ID 891115
Reference URL
Back to Search Results