Prostatic carcinoma metastasis in bone marrow of sternum (human)

Stain: Hematoxylin and eosin. Survey (A) and detail (B) of a prostate carcinoma metastasized to the bone marrow, (sternum aspiration). Clusters of tumour cells; clearly foreign to the marrow. Common primary tumours that metastasize to the bone marrow include breast, prostate, lung, thyroid, kidney, bladder and uterus and, in children, neuroblastoma. Immunohistochemistry and enzyme histochemistry may helpful in differential diagnosis.