Keratin staining of bronchus epithelium (human, adult)

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Title Keratin staining of bronchus epithelium (human, adult)
Creator Poels, Lambert G.
Contributor Lambert G. Poels, PhD, UMC St Radboud Nijmegen; Paul H. K. Jap, PhD, UMC St Radboud Nijmegen
Date 2006-09-28
Subject Bronchial epithelium; Keratin antibodies; Tumor diagnosis
Description Stain: Anti-keratin-5-7-14-19 (OVTL 12/5 monoclonal antibody with immunoperoxidase staining on frozen sections). The pseudostratified epithelium (1) is stained keratin-positively (brown product) as well as the epithelial derivates such as the bronchial glands (2) and their excretory ducts (3). Other structures react negatively (blue stain) such as blood vessels (4), slender bundles of smooth muscles (5, subepithelially), and cellular infiltrations of non-epithelial origin. This particular antibody against a certain epitope of the keratin filament protein family is applicable in the diagnosis of epithelial-derived tumours (e.g. carcinoma) versus non-epithelial-derived tumours (e.g. sarcoma).
Subtype Image
Format image/jpeg
Collection Poja Histology Collection - Respiratory System Subset
ARK ark:/87278/s6zg9vfm
Setname ehsl_heal
Date Created 2012-12-11
Date Modified 2012-12-11
ID 890790
Reference URL