Lamellar body of a type II alveolar cell in the lung (dog)

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Title Lamellar body of a type II alveolar cell in the lung (dog)
Creator Poels, Lambert G.
Contributor Lambert G. Poels, PhD, UMC St Radboud Nijmegen; Paul H. K. Jap, PhD, UMC St Radboud Nijmegen
Date 2006-09-28
Subject Type II alveolar cell; Pneumocyte II; Multilamellar bodies; Cytosomes; Tubular myelin
Description Electron microscopy. Extrusion of surfactant material out of a type II alveolar cell (pneumocyte II, great alveolar cell). After fusion of a multilamellar body (1) (cytosome) with the apical cell membrane (note microvilli 2) the electron-dense lamellar content or surfactant (consisting of phosphatidylcholine, phosphoglycerol, cholesterol and SP-proteins) will be discharged. After release the secretion spreads over the alveolar surface and forms an extracellular coating. This detergent reduces the surface tension at the air-fluid interface, it also contributes to stabilize alveolar diameters. At (*) remnants of surfactant the so-called tubular myelin (after adequate fixation). Several packed lamellae resemble stacks of the crystalline phase of a polar lipid-water system.
Subtype Image
Format image/jpeg
Collection Poja Histology Collection - Respiratory System Subset
ARK ark:/87278/s6t75kqq
Setname ehsl_heal
Date Created 2012-12-11
Date Modified 2012-12-11
ID 890706
Reference URL
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