Title |
Lamellar body of a type II alveolar cell in the lung (dog) |
Creator |
Poels, Lambert G. |
Contributor |
Lambert G. Poels, PhD, UMC St Radboud Nijmegen; Paul H. K. Jap, PhD, UMC St Radboud Nijmegen |
Date |
2006-09-28 |
Subject |
Type II alveolar cell; Pneumocyte II; Multilamellar bodies; Cytosomes; Tubular myelin |
Description |
Electron microscopy. Extrusion of surfactant material out of a type II alveolar cell (pneumocyte II, great alveolar cell). After fusion of a multilamellar body (1) (cytosome) with the apical cell membrane (note microvilli 2) the electron-dense lamellar content or surfactant (consisting of phosphatidylcholine, phosphoglycerol, cholesterol and SP-proteins) will be discharged. After release the secretion spreads over the alveolar surface and forms an extracellular coating. This detergent reduces the surface tension at the air-fluid interface, it also contributes to stabilize alveolar diameters. At (*) remnants of surfactant the so-called tubular myelin (after adequate fixation). Several packed lamellae resemble stacks of the crystalline phase of a polar lipid-water system. |
Subtype |
Image |
Format |
image/jpeg |
Rights |
http://creativecommons.org/licenses/by-nc-nd/2.5/ |
Collection |
Poja Histology Collection - Respiratory System Subset |
ARK |
ark:/87278/s6t75kqq |
Setname |
ehsl_heal |
ID |
890706 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6t75kqq |