Keratin 7 in the lining alveolar epithelium of the lung (human, adult)

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Title Keratin 7 in the lining alveolar epithelium of the lung (human, adult)
Creator Poels, Lambert G.
Contributor Lambert G. Poels, PhD, UMC St Radboud Nijmegen; Paul H. K. Jap, PhD, UMC St Radboud Nijmegen
Date 2006-09-28
Subject Pneumocyte I; Pneumocyte II; Imunoperoxidase; Immuno-reaction
Description Stain: anti-keratin 7 antibody (Pan-Ck 7) immunoperoxidase staining (with aminoethylcarbazole (AEC) substrate). Both alveolar epithelial cell types I (1) and II (2) stain dark brown-red after the reaction with AEC indicating a positive reaction for cytokeratin 7. Note the white (non-stained) capillaries (↓) sandwiched between the red-brown reacting alveolar epithelial cells (air-blood exchange). Within the alveolar lumen alveolar macrophages (M) appear negative for keratin 7. This antibody can be used in the study of alveolar developmental processes in the lung, or of various types of bronchial carcinoma as well in the differential diagnosis between various types of carcinoma in the lungs.
Subtype Image
Format image/jpeg
Collection Poja Histology Collection - Respiratory System Subset
ARK ark:/87278/s6gx7dtj
Setname ehsl_heal
Date Created 2012-12-11
Date Modified 2012-12-11
ID 890693
Reference URL
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