Title |
Keratin 7 staining in dysplastic epithelium of a bronchus (human, adult) |
Creator |
Poels, Lambert G. |
Contributor |
Lambert G. Poels, PhD, UMC St Radboud Nijmegen; Paul H. K. Jap, PhD, UMC St Radboud Nijmegen |
Date |
2006-09-28 |
Subject |
Immunoperoxidase; Immuno-reaction |
Description |
Stain: anti-keratin 7 antibody (Pan-Ck 7) immunoperoxidase staining (with aminoethylcarbazole (AEC) substrate). A red-brown staining with AEC indicates a positive reaction for cytokeratin 7. Disturbances in the growth and maturing might result in dysplasia of the epithelium with a changed reaction pattern for among others cytokeratins. In this mild dysplastic bronchial epithelium the reactivity for keratin 7 appears lost completely. This antibody is considered as useful in the study of premalignant changes in complex epithelia (e.g., pseudostratified, squamous stratified epithelia) within the lungs, cervix, etc. |
Subtype |
Image |
Format |
image/jpeg |
Rights |
http://creativecommons.org/licenses/by-nc-nd/2.5/ |
Collection |
Poja Histology Collection - Respiratory System Subset |
ARK |
ark:/87278/s6ns3x4f |
Setname |
ehsl_heal |
ID |
890653 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6ns3x4f |