| Identifier |
20240303_nanos_posters_169 |
| Title |
A Rare Case of SMARCA4-Deficient Undifferentiated Thoracic Tumor Presenting with Headache and Hallucinations |
| Creator |
Aishwarya Sriram; Bardia Abbasi; Dean Cestari |
| Affiliation |
(AS) Moran Eye Center; (BA) (DC) Massachusetts Eye and Ear/Harvard Medical School |
| Subject |
Tumors; Neuro-ophth & Systemic Disease ( eg. MS, MG, thyroid); Visual Fields; Neuroimaging |
| Description |
SMARCA4-deficient undifferentiated thoracic tumors are novel tumors first described in 2015, with limited reported cases to date. They typically occur in male middle-aged smokers and are highly aggressive. They can be metastatic on presentation, most commonly to the lymph nodes, bones, or adrenal glands. We present a unique case of metastatic SMARCA4-deficient thoracic tumor, in which the initial symptoms were headaches and visual hallucinations. |
| Date |
2024-03 |
| References |
Roden AC. Thoracic SMARCA4-deficient undifferentiated tumor-a case of an aggressive neoplasm-case report. Mediastinum. 2021 Dec 25;5:39. doi: 10.21037/med-20-15. PMID: 35118344; PMCID: PMC8794332. Al-Shbool G, Krishnan Nair H. SMARCA4-Deficient Undifferentiated Tumor: A Rare Malignancy With Distinct Clinicopathological Characteristics. Cureus. 2022 Oct 26;14(10):e30708. doi: 10.7759/cureus.30708. PMID: 36439610; PMCID: PMC9694527. Sauter JL, Graham RP, Larsen BT, Jenkins SM, Roden AC, Boland JM. SMARCA4-deficient thoracic sarcoma: a distinctive clinicopathological entity with undifferentiated rhabdoid morphology and aggressive behavior. Mod Pathol. 2017 Oct;30(10):1422-1432. doi: 10.1038/modpathol.2017.61. Epub 2017 Jun 23. PMID: 28643792. Koizumi A, Tamura Y, Yoshida R, Mori C, Ono Y, Tanino M, Mizukami Y, Sasaki T. Two Cases of SMARCA4-Deficient Non-small Cell Lung Cancer (NSCLC) with Improved Performance Status (PS) after Treatment with Immune Checkpoint Inhibitors (ICIs). Cureus. 2023 Apr 16;15(4):e37656. doi: 10.7759/cureus.37656. PMID: 37200668; PMCID: PMC10188218. Yadav R, Sun L, Salyana M, Eric M, Gotlieb V, Wang JC. SMARCA4-Deficient Undifferentiated Tumor of Lung Mass-A Rare Tumor With the Rarer Occurrence of Brain Metastasis: A Case Report and Review of the Literature. J Investig Med High Impact Case Rep. 2022 Jan-Dec;10:23247096221074864. doi: 10.1177/23247096221074864. PMID: 35356840; PMCID: PMC8978313 |
| Language |
eng |
| Format |
application/pdf |
| Type |
Text |
| Source |
2024 North American Neuro-Ophthalmology Society Annual Meeting |
| Relation is Part of |
NANOS Annual Meeting 2024: Poster Session: Descriptive Studies I: Disorders of the Posterior Visual Pathway and Visual Processing |
| Collection |
Neuro-Ophthalmology Virtual Education Library: NANOS Annual Meeting Collection: https://novel.utah.edu/collection/nanos-annual-meeting-collection/ |
| Publisher |
North American Neuro-Ophthalmology Society |
| Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management |
Copyright 2024. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
| ARK |
ark:/87278/s6tr609k |
| Setname |
ehsl_novel_nam |
| ID |
2594009 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6tr609k |
