Evaluation of the effects of the toxicant carbon monoxide on Dravet syndrome pathophysiology

Update Item Information
Publication Type poster
School or College College of Pharmacy
Department Pharmacology & Toxicology
Author Simpson, Taylor; Hari, Ashwini Sri; Metcalf, Cameron S.
Title Evaluation of the effects of the toxicant carbon monoxide on Dravet syndrome pathophysiology
Date 2024
Description There is no literature on the impacts of CO on the Dravet Syndrome population • The aim of this study is to better understand how sub-chronic CO exposure influences Dravet Syndrome pathophysiology. • About 80% of DS patients have a Scn1a gene mutation1, so our model is C57 Black mice with an Scn1aA1783V/WT missense mutation. • If a Dravet patient goes out during a period of high pollution, they could be at high risk
Type Text
Publisher University of Utah
Subject dravite syndrome; epilepsy; air pollution; metabolomics; carbon monoxide; mouse model; neuroscience
Language eng
Rights Management (c) Taylor Simpson; Ashwini Sri Hari; Cameron S. Metcalf
Format Medium application/pdf
ARK ark:/87278/s6r3a93y
Setname ir_uw
ID 2470394
Reference URL https://collections.lib.utah.edu/ark:/87278/s6r3a93y
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