| Title |
Retinal Input to the Primate Lateral Geniculate Nucleus Revealed by Injection of a Different Label Into Each Eye |
| Creator |
Zachary R. Spahr. John R. Economides; Jonathan C; Horton |
| Affiliation |
College of Medicine (ZRS), State University of New York, Upstate Medical University, Syracuse, New York; and Department of Ophthalmology (JRE, JCH), University of California, San Francisco, San Francisco, California |
| Abstract |
The primate lateral geniculate nucleus has long been a favorite structure among anatomists because of its striking lamination. It has been shown that each lamina receives input from a different eye using various single label techniques but never by double labeling. Here, we illustrate the organization of retinal inputs to the lateral geniculate nucleus by injection of cholera toxin-B conjugated to Alexa Fluor-488 into the right eye and cholera toxin-B conjugated to Alexa Fluor-594 into the left eye. |
| Subject |
Animals; Cholera Toxin; Geniculate Bodies; Primates; Retina; Visual Pathways |
| Date |
2022-12 |
| Date Digital |
2022-12 |
| References |
1. Minkowski M. Über den verlauf, die endigung und die zentrale repräsentation von gekreuzten und ungekreuzten sehnervenfasern bei einigen säugetieren und beim menschen. Schweiz Arch f Neurol u Psychiat. 1920;6:201-252. 2. Wiesel TN, Hubel DH, Lam DMK. Autoradiographic demonstration of ocular-dominance columns in the monkey striate cortex by means of transneuronal transport. Brain Res. 1974;79:273-279. - PubMed. 3. Horton JC, Hedley-Whyte ET. Mapping of cytochrome oxidase patches and ocular dominance columns in human visual cortex. Philos Trans R Soc Lond B Biol Sci. 1984;304:255-272. - PubMed. 4. Kennedy C, Des Rosiers MH, Sakurada O. Metabolic mapping of the primary visual system of the monkey by means of the autoradiographic 14[c] deoxyglucose technique. Proc Natl Acad Sci USA. 1976;73:4230. - PMC - PubMed. 5. Hendry SH. Delayed reduction in GABA and GAD immunoreactivity of neurons in the adult monkey dorsal lateral geniculate nucleus following monocular deprivation or enucleation. Exp Brain Res. 1991;86:47-59. - PubMed. |
| Language |
eng |
| Format |
application/pdf |
| Type |
Text |
| Publication Type |
Journal Article |
| Source |
Journal of Neuro-Ophthalmology, December 2022, Volume 42, Issue 4 |
| Collection |
Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/ |
| Publisher |
Lippincott, Williams & Wilkins |
| Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management |
© North American Neuro-Ophthalmology Society |
| ARK |
ark:/87278/s6117f91 |
| Setname |
ehsl_novel_jno |
| ID |
2392991 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6117f91 |
