MS and the Immune System

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Identifier 20230315_nanos_neuroimmunology1_01
Title MS and the Immune System
Creator Jennifer Graves, MD, PhD, MAS
Affiliation UCSD, San Diego, CA
Subject Multiple Sclerosis; Autoimmunity; Genetics; Aging; Sex Differences
Description Multiple sclerosis is a multifactorial autoimmune disease of the central nervous system with three primary targets of the brain, spinal cord and optic nerves. Based on monozygotic twin studies, the heritability of MS is 25%.
Date 2023-03
References 1. International MS Genetics Consortium. Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility Science 2019. Vol 365; No. 6460. Sept 27. 2. Fitzgerald, KC, et al. Early complement genes are associated with visual system degeneration in multiple sclerosis. Brain 2019. Vol 142. Pages 2722-2736. Sept 1. 3. Attfield, KE, Jensen, LT, kaufman, M, Friese, MA, Fugger, L. The Immunology of Multiple Sclerosis. Nature Reviews Immunology 2022. May 4th. 4. Graves, JS, Krysko, KM, Hua, LH, Absinta, M, Franklin, JM, Segal, BM. Ageing and Multiple Sclerosis. Lancet Neurology. Oct 7 2022. Online First. 5. Krysko KM, Henry RG, Cree BAC, et al. Telomere length is associated with disability progression in multiple sclerosis. Ann Neurol 2019; 86: 671-82.
Language eng
Format video/mp4
Type Image/MovingImage
Source 49th Annual North American Neuro-Ophthalmology Society Annual Meeting
Relation is Part of NANOS Annual Meeting 2023: Neuroimmunology: https://novel.utah.edu/collection/NAM/toc/
Collection Neuro-Ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
Publisher North American Neuro-Ophthalmology Society
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah, 10 N 1900 E SLC, UT 84112-5890
Rights Management Copyright 2023. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright
ARK ark:/87278/s618z2fn
Setname ehsl_novel_nam
ID 2386003
Reference URL https://collections.lib.utah.edu/ark:/87278/s618z2fn
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