Assessing the Impact of Idebenone in Leber's Hereditary Optic Neuropathy According to Primary Mitochondrial DNA Mutation: Results From the LEROS Study
Creator
Nancy Newman; Lorena Castillo Campillo; Livia Tomasso; Patrick Yu-Wai-Man; Valerio Carelli; Thomas Klopstock
Affiliation
(NN) Departments of Ophthalmology, Neurology, and Neurological Surgery, Emory University School of Medicine; (LCC) Institut Catala de Retina SL; (LTT) Chiesi Farmaceutici SpA; (PY) Department of Clinical Neurosciences, University of Cambridge; (PC) IRCCS Istituto delle Scienze Neurologiche di Bologna; (TK) Friedrich-Baur-Institut
Subject
Genetic Disease; Optic Neuropathy; Retina
Description
In LEROS, visual acuity (VA) outcomes following 24 months of idebenone treatment were compared to an external, matched, natural history (NH) cohort. Here, we report VA outcome results from LEROS according to primary mitochondrial DNA (mtDNA) mutation.
Date
2023-03
References
None provided.
Language
eng
Format
video/mp4
Type
Image/MovingImage
Source
49th Annual North American Neuro-Ophthalmology Society Annual Meeting
