Glucagon-Like Peptide-1 and Lipid Metabolism Are Associated With a Reduction in Intracranial Pressure in Idiopathic Intracranial Hypertension
Creator
Zerin Alimajstorovic; James L. Mitchell; Andreas Yiangou; Thomas Hancox; Andrew Southam; Olivia Grech; Ryan Ottridge; Catherine Winder; Abd Tahrani; Tricia Tan; Susan Mollan; Warwick Dunn; Alexandra Sinclair
Affiliation
(ZA) (JLM) (AY) (TH) (AS) (OG) (RO) (CW) (AT) (SM) (AS) University of Birmingham; (TT) Imperial College London; (WD) University of Liverpool
Subject
High Intracranial Pressure/Headache
Description
Idiopathic intracranial hypertension (IIH), a disease classically occurring in women with obesity, is characterised by raised intracranial pressure (ICP). Weight loss leads to reduction in ICP. Glucagon-like peptide 1 (GLP-1) agonism reduces cerebrospinal fluid (CSF) secretion and ICP. The potential mechanisms by which weight loss reduces ICP are unknown and was the focus for this study.
Date
2023-03
References
None provided.
Language
eng
Format
video/mp4
Type
Image/MovingImage
Source
49th Annual North American Neuro-Ophthalmology Society Annual Meeting
