(TK) (MP) (KG) Keck School of Medicine of USC; (SM) (PL) (PY) (EI) (BT) (MS) (GL) University of Southern California
Subject
Optic Nerve Trauma and Treatment; Miscellaneous
Description
Regenerating the optic nerve requires signals that both "fuel" and "steer" retinal ganglion cell (RGC) axon growth to appropriate targets. Although strategies to increase mammalian target of rapamycin (mTOR) activity have been employed to "fuel" RGC axon regeneration, they are not as effective at "steering" regeneration. Based on compelling evidence that electric field (EF) application does both, we investigated whether EFs-in conjunction with mTOR activation-direct more target-specific RGC axon regeneration than either treatment alone.
Date
2023-03
References
None provided.
Language
eng
Format
video/mp4
Type
Image/MovingImage
Source
49th Annual North American Neuro-Ophthalmology Society Annual Meeting
