| Identifier |
20230314_nanos_posters_280 |
| Title |
Quantifying Retrograde Trans-Synaptic Degeneration of the Visual Pathway in Multiple Sclerosis |
| Creator |
Sargis Manukyan; Gabriela Zabala; Laura Locke; Brooke Guerrero; Marwa Kaisey; Afshin Khodabakhsh; Aaron Carass; Jerry Prince; Shiv Saidha; Peter Calabresi; Nancy Sicotte; Pascal Sati; Omar Al-Louzi |
| Affiliation |
(SM) (GZ) (OA) Visual Outcomes Laboratory, Cedars-Sinai Medical Center; (LL) (BG) (MK) (NS) Department of Neurology, Cedars-Sinai Medical Center; (AK) Department of Ophthalmology, Cedars-Sinai Medical Center; (AC) (JP) Department of Electrical and Computer Engineering, Johns Hopkins University; (SS) (PC) Division of Neuroimmunology and Neurological Infections, Department of Neurology, Johns Hopkins University; (PS) Neuroimaging Program, Department of Neurology, Cedars-Sinai Medical Center |
| Subject |
Neuro-ophth & Systemic Disease (eg. MS, MG, Thyroid); Demeylinating Disease; Visual Fields, Retina; Diagnostic Tests (ERG, VER, OCT, HRT, mfERG, etc) |
| Description |
Neurodegeneration occurs early in multiple sclerosis (MS), contributes to irreversible clinical disability, and is poorly mitigated by currently available treatments. Retrograde trans-synaptic degeneration (rTSD) is a phenomenon in which injury to one neuroaxonal unit propagates retrogradely, amplifying neuronal loss from MS lesions. No effective ways of quantifying rTSD in the visual pathway or its impact on visual function have been performed. The objectives of this study were to quantify rTSD in MS and investigate its association with clinical characteristics and visual function. |
| Date |
2023-03-14 |
| Language |
eng |
| Format |
application/pdf |
| Type |
Text |
| Source |
2023 North American Neuro-Ophthalmology Society Annual Meeting |
| Relation is Part of |
NANOS Annual Meeting 2023: Poster Session II: Neuro-Ophthalmic Disorders of Neurologic and Systemic Diseases |
| Collection |
Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu |
| Publisher |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Holding Institution |
North American Neuro-Ophthalmology Association. NANOS Executive Office 5841 Cedar Lake Road, Suite 204, Minneapolis, MN 55416 |
| Rights Management |
Copyright 2023. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
| ARK |
ark:/87278/s6kcbk42 |
| Setname |
ehsl_novel_nam |
| ID |
2335485 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6kcbk42 |
