Secondary Pseudotumor Cerebri in a Patient Undergoing Treatment with All-trans-retinoic acid and Arsenic Trioxide

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Identifier 20230312_nanos_posters_150
Title Secondary Pseudotumor Cerebri in a Patient Undergoing Treatment with All-trans-retinoic acid and Arsenic Trioxide
Creator Anupam Garg; Gabriel Ghiaur; Amanda Henderson
Affiliation (AG) Wilmer Eye Insitute, Johns Hopkins University; (GG) Sidney Kimmel Cancer Center, Johns Hopkins University; (AH) Wilmer Eye Institute, Johns Hopkins
Subject Pseudotumor Cerebri; High Intracranial Pressure/Headache; Chemotherapy and Radiation Injury
Description Treatment with all-trans-retinoic acid (ATRA) and arsenic trioxide (ATO) has emerged as standard therapy for patients with acute promyelocytic anemia (APL), with randomized trials demonstrating complete remission in up to 100% of patients (1,2). Previous studies have demonstrated increased risk of pseudotumor cerebri (PTC) with ATRA therapy (3,4), but there are limited data assessing the risk of PTC with ATRA/ATO therapy. A previous case series of 10 patients treated with ATRA/ATO demonstrated an incidence of 50% (5), suggesting a higher rate than in patients treated with ATRA alone.
Date 2023-03-14
Language eng
Format application/pdf
Type Text
Source 2023 North American Neuro-Ophthalmology Society Annual Meeting
Relation is Part of NANOS Annual Meeting 2023: Poster Session I: Idiopathic Intracranial Hypertension (IIH)
Collection Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
Publisher Spencer S. Eccles Health Sciences Library, University of Utah
Holding Institution North American Neuro-Ophthalmology Association. NANOS Executive Office 5841 Cedar Lake Road, Suite 204, Minneapolis, MN 55416
Rights Management Copyright 2023. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright
ARK ark:/87278/s66df2kd
Setname ehsl_novel_nam
ID 2335356
Reference URL https://collections.lib.utah.edu/ark:/87278/s66df2kd
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