Concurrent Paraneoplastic Neuromyelitis Optica and Lambert-Eaton Myasthenic Syndrome

Update Item Information
Identifier 20230312_nanos_posters_002
Title Concurrent Paraneoplastic Neuromyelitis Optica and Lambert-Eaton Myasthenic Syndrome
Creator Haley D'Souza; M. Tariq Bhatti; Andrew McKeon; John Chen; Deena Tajfirouz
Affiliation (HD) (MTB) (AM) (JC) Mayo Clinic; (DT) Mayo Clinic - Rochester, MN
Subject Paraneoplastic Syndromes; Optic Neuropathy
Description Lambert-Eaton Myasthenic Syndrome (LEMS) is uncommon and associated with small cell lung cancer (SCLC). Neuromyelitis optica spectrum disorder (NMOSD) is rare, and has also been reported in association with malignancy, most commonly, breast adenocarcinoma. We present a case of concurrent paraneoplastic LEMS and NMOSD due to underlying malignancy, which is an association that has not been previously reported.
Date 2023-03-12
References Hor JY, Asgari N, Nakashima I, Broadley SA, Leite MI, et al. Epidemiology of Neuromyelitis Optica Spectrum Disorder and Its Prevalence and Incidence Worldwide. Front Neurol. 2020 Jun 26;11:501. doi: 10.3389/fneur.2020.00501. PMID: 32670177; PMCID: PMC7332882. Shahmohammadi S, Doosti R, Shahmohammadi A, Azimi A, Sahraian MA, et al. Neuromyelitis optica spectrum disorder (NMOSD) associated with cancer: A systematic review. Mult Scler Relat Disord. 2021 Nov;56:103227. doi: 10.1016/j.msard.2021.103227. Epub 2021 Aug 27. PMID: 34536774. Jarius S, Frederikson J, Waters P, Paul F, Akman-Demir G, et al. Frequency and prognostic impact of antibodies to aquaporin-4 in patients with optic neuritis, Journal of the Neurological Sciences, Volume 298, Issues 1-2, 2010, Pages 158-162, ISSN 0022-510X. Yuan J, Jia Z, Qin W, Hu W. Paraneoplastic neuromyelitis optica spectrum disorder associated with breast cancer. Clin Interv Aging. 2019 Jun 6;14:1039-1044. doi: 10.2147/CIA.S202102. PMID: 31239653; PMCID: PMC6559253.
Language eng
Format application/pdf
Type Text
Source 2023 North American Neuro-Ophthalmology Society Annual Meeting
Relation is Part of NANOS Annual Meeting 2023: Poster Session I: Disorders of the Anterior Visual Pathway (Retina, Optic Nerve, and Chiasm)
Collection Neuro-Ophthalmology Virtual Education Library: NANOS Annual Meeting Collection: https://novel.utah.edu/collection/nanos-annual-meeting-collection/
Publisher North American Neuro-Ophthalmology Society
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management Copyright 2023. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright
ARK ark:/87278/s6shhbhj
Setname ehsl_novel_nam
ID 2335209
Reference URL https://collections.lib.utah.edu/ark:/87278/s6shhbhj
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