MS and the Immune System

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Identifier 20230315_nanos_neuroimmunology1_01
Title MS and the Immune System
Creator Jennifer Graves, MD, PhD, MAS
Affiliation UCSD, San Diego, CA
Subject Multiple Sclerosis; Autoimmunity; Genetics; Aging; Sex Differences
Description Multiple sclerosis is a multifactorial autoimmune disease of the central nervous system with three primary targets of the brain, spinal cord and optic nerves. Based on monozygotic twin studies, the heritability of MS is 25%. Over the last decade of advances in genome wide association studies, 48% of that heritability has now been explained by > 200 MS risk alleles, the majority of which are associated with immune genes. The closest genetic cousins of MS are other autoimmune diseases and not neurodegenerative diseases.
Date 2023-03
Language eng
Format application/pdf
Type Text
Source 2023 North American Neuro-Ophthalmology Society Annual Meeting
Relation is Part of NANOS Annual Meeting 2023: Neuroimmunology
Collection Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
Publisher Spencer S. Eccles Health Sciences Library, University of Utah
Holding Institution North American Neuro-Ophthalmology Association. NANOS Executive Office 5841 Cedar Lake Road, Suite 204, Minneapolis, MN 55416
Rights Management Copyright 2023. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright
ARK ark:/87278/s6wk9wtf
Context URL The NANOS Annual Meeting Neuro-Ophthalmology Collection: https://novel.utah.edu/collection/NAM/toc/
Contributor Primary Jennifer Graves, MD, PhD, MAS
Setname ehsl_novel_nam
ID 2309965
Reference URL https://collections.lib.utah.edu/ark:/87278/s6wk9wtf
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