Title |
Damage to the Optic Radiation in Patients With MIid Traumatic Brain Injury |
Creator |
Sung Ho Jang; Jeong Pyo Seo |
Abstract |
BACKGROUND: There are known limitations of conventional computed tomography and magnetic resonance imaging in detecting neural injury in patients with mild traumatic brain injury (TBI). Diffusion tensor imaging (DTI) provides a method to further assess cerebral injury in this patient population. We report 2 patients with mild TBI who showed injury of the optic radiation (OR) as demonstrated by DTI. METHOD: Two patients who complained of visual field loss after mild TBI and 9 age-matched normal control subjects were recruited for this study. Peripheral field defects were detected with automated perimetry in both patients. RESULTS: Regarding the configuration of OR, the total volume of OR was decreased in the right OR of both patients compared with controls; in contrast, the left ORs were divided into 2 parts in both patients. The voxel numbers of both ORs in both patients were more than 2 standard deviations lower than that of normal control subjects. The apparent diffusion coefficient value of the right OR in patient 2 was more than 2 standard deviations higher than that of normal controls. CONCLUSIONS: We demonstrated injury of the OR using DTI in 2 patients who showed visual field defects after mild TBI. |
Subject |
Adult; Brain Injuries; Case-Control Studies; Diffusion Tensor Imaging; Female; Humans; Male; Middle Older people; Neuropsychological Tests; Optic Nerve Diseases; Vision Disorders; Visual Field Tests |
Format |
application/pdf |
Publication Type |
Journal Article |
Collection |
Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/ |
Publisher |
Lippincott, Williams & Wilkins |
Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
Rights Management |
© North American Neuro-Ophthalmology Society |
Setname |
ehsl_novel_jno |
ID |
227744 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s62j9hxc/227744 |