Intravitreal Bevacizumab in the Treatment of Peripapillary Choroidal Neovascular Membrane Secondary to Idiopathic Intracranial Hypertension

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Title Intravitreal Bevacizumab in the Treatment of Peripapillary Choroidal Neovascular Membrane Secondary to Idiopathic Intracranial Hypertension
Creator In-Jung Lee, BSc, BAppSc, MBBS; Luke J. Maccheron, BMedSc, MBBS, FRANZCO; Anthony S. Kwan, MBChB, MD, FRCOphth, FRANZCO
Affiliation Mater Adult Hospital, South Brisbane, Queensland, Australia; School of Medicine, Faculty of Healthy Sciences, University of Queensland, Queensland, Australia
Abstract A 14 year-old Caucasian boy with idiopathic intracranial hypertension (IIH) presented with blurred vision in his left eye. Visual acuity was 20/20, right eye, and 20/80, left eye, and funduscopy revealed bilateral papilledema. In addition, there was peripapillary choroidal neovascular membrane (PPCNVM) in the left eye. Oral acetazolamide improved the symptoms and signs of IIH, but seven weeks later, acuity remained 20/80, left eye, with an increase in subretinal hemorrhage. Two weeks following an intravitreal injection of bevacizumab, visual acuity on the left had improved to 20/30 with resolution of subretinal hemorrhage and fibrosis of PPCNVM. After an additional 2 weeks, visual acuity improved to 20/20, and there has been no sign of recurrence over 3.5 years of follow-up.
Subject Acetazolamide / therapeutic use; Adolescent; Angiogenesis Inhibitors / adverse effects; Antibodies, Monoclonal, Humanized / adverse effects; Bevacizumab; Carbonic Anhydrase Inhibitors / therapeutic use; Choroidal Neovascularization / complications; Choroidal Neovascularization / drug therapy; Fluorescein Angiography; Humans; Intravitreal Injections; Male; Papilledema / complications; Papilledema / drug therapy; Pseudotumor Cerebri / chemically induced; Visual Acuity
OCR Text Show
Date 2013-06
Language eng
Format application/pdf
Type Text
Publication Type Journal Article
Collection Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/
Publisher Lippincott, Williams & Wilkins
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management © North American Neuro-Ophthalmology Society
ARK ark:/87278/s61r9wpj
Setname ehsl_novel_jno
ID 227397
Reference URL https://collections.lib.utah.edu/ark:/87278/s61r9wpj
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