| Title |
Schilder's myelinoclastic diffuse sclerosis. |
| Creator |
Lana-Peixtoto, M.A.; dos Santos, E.C. |
| Affiliation |
Department of Neurology, Federal University of Minas Gerais Medical School, Belo Horizonte, Brazil. |
| Abstract |
We report here a case of Schilder's myelinoclastic diffuse sclerosis in a 14-year-old girl with sudden bilateral visual loss. Computed tomographic scan showed two large symmetrical lesions in the occipital lobes and a smaller hypodense area in the frontal lobe. Cerebrospinal fluid examination revealed increased immunoglobulin G fraction with the presence of oligoclonal bands. Ultrastructural study of a biopsy specimen disclosed a demyelinating disorder with no cytoplasmic inclusions. Steroid treatment was followed by a dramatic response, with almost complete visual recovery and shrinkage of the lesions. |
| Subject |
Adolescent; Dexamethasone; Diffuse Cerebral Sclerosis of Schilder; Female; Humans; Occipital Lobe; Tomography, X-Ray Computed; Vision Disorders |
| Format |
application/pdf |
| Publication Type |
Journal Article |
| Collection |
Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/ |
| Publisher |
Lippincott, Williams & Wilkins |
| Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management |
© North American Neuro-Ophthalmology Society |
| Setname |
ehsl_novel_jno |
| ID |
226342 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s60c81th/226342 |
