| Title |
Idiopathic hypertrophic cranial pachymeningitis. |
| Creator |
Hamilton, S.R.; Smith, C.H.; Lessell, S. |
| Affiliation |
Division of Neurology, University of Washington, Seattle. |
| Abstract |
We evaluated 3 patients with biopsy-proven hypertrophic cranial pachymeningitis apparently unrelated to any systemic disease. Each patient had chronic headache, cranial neuropathy, an elevated ESR, and a mild CSF pleocytosis. Neuro-ophthalmic findings included bilateral sixth nerve palsies in two patients and the third had bilateral optic neuropathies. MR imaging revealed thickened dura that enhanced with Gd-DTPA administration. Histologic examination showed thickened, fibrotic dura with a sterile, chronic, nongranulomatous inflammation. The response to treatment was variable with corticosteroids, immunosuppressive drugs, or radiation. The distinctive MR appearance should help physicians recognize this rarely reported disease. |
| Subject |
Abdducens Nerve; Adult; Older people; Contrast Media; Cranial Nerve Diseases; Dura Mater; Encephalitis; Female; Gadolinium; Gadolinium DTPA; Headache; Humans; Hypertrophy; Magnetic Resonance Imaging; Male; Middle Older people; Optic Nerve Diseases; Organometallic Compounds; Paralysis; Pentetic Acid |
| Format |
application/pdf |
| Publication Type |
Journal Article |
| Collection |
Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/ |
| Publisher |
Lippincott, Williams & Wilkins |
| Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management |
© North American Neuro-Ophthalmology Society |
| Setname |
ehsl_novel_jno |
| ID |
225864 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6k96dm6/225864 |
