| Title |
Glioblastoma multiforme masquerading as pseudotumor cerebri. Case report. |
| Creator |
Aroichane, M.; Miller, N.R.; Eggenberger, E.R. |
| Affiliation |
Neuro-Ophthalmology Unit, Johns Hopkins Medical Institution, Baltimore, Maryland. |
| Abstract |
A 16-year-old girl developed headaches and bilateral papilledema while taking minocycline for acne. The initial neuro-ophthalmologic evaluation was normal except for enlarged blind spots OU. An MRI scan demonstrated subtle abnormalities. A lumbar puncture was entirely normal except for an increased opening pressure. A tentative diagnosis of pseudotumor cerebri was made and the patient was treated with Diamox. A second MRI was unchanged, and a lumbar puncture performed while the patient was taking Diamox was entirely normal. The patient subsequently lost vision in both eyes, and a third MRI now revealed a supracellar enhancing mass. Biopsy and subtotal resection of the mass showed it to be a glioblastoma multiforme. This case emphasizes pitfalls in the diagnosis of pseudotumor cerebri. Careful follow-up and a high index of suspicion in pseudotumor cerebri syndromes are essential. |
| Subject |
Adolescent; Brain Neoplasms; Diagnosis, Differential; Female; fundus Oculi; Glial Fibrillary Acidic Protein; Gioblastoma; Humans; Magnetic Resonance Imaging; Minocycline; Papilledema; Pseudotumor Cerebri; Visual Fields |
| Format |
application/pdf |
| Publication Type |
Journal Article |
| Collection |
Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/ |
| Publisher |
Lippincott, Williams & Wilkins |
| Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management |
© North American Neuro-Ophthalmology Society |
| Setname |
ehsl_novel_jno |
| ID |
225860 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6k96dm6/225860 |
