Good Visual Outcomes After Pituitary Tumor Surgery Are Associated With Increased Visual Cortex Functional Connectivity

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Title Good Visual Outcomes After Pituitary Tumor Surgery Are Associated With Increased Visual Cortex Functional Connectivity
Creator Stefan T. Lang, MD; Won Hyung A. Ryu, MD, MSc, MTM; Yves P. Starreveld, MD, PhD; Fiona E. Costello, MD; the PITNET Study Group
Affiliation Division of Neurosurgery (STL, WHAR, YPS), Department of Clinical Neurosciences, Cumming School of Medicine, University of Calgary, Calgary, Canada; Division of Ophthalmology (FEC), Department of Surgery, Cumming School of Medicine, University of Calgary, Cal- gary, Canada; Division of Neurology (FEC), Department of Clinical Neurosciences, Cumming School of Medicine, University of Calgary, Calgary, Canada; Department of Neurological Surgery (WHAR), Rush University, Chicago, IL; and Hotchkiss Brain Institute (STL, FEC), University of Calgary, Calgary, Canada
Abstract Patients presenting with visual impairment secondary to pituitary macroadenomas often experience variable recovery after surgery. Several factors may impact visual outcomes including the extent of neuroaxonal dam- age in the afferent visual pathway and cortical plasticity. Optical coherence tomography (OCT) measures of retinal structure and resting-state functional MRI (rsfMRI) can be used to evaluate the impact of neuroaxonal injury and cor- tical adaptive processes, respectively. The purpose of this study was to determine whether rsfMRI patterns of func- tional connectivity (FC) distinguish patients with good vs poor visual outcomes after surgical decompression of pituitary adenomas.
Subject Vision Loss; Pituitary Macroadenomas; Surgical Decompression
OCR Text Show
Date 2021-12
Language eng
Format application/pdf
Type Text
Publication Type Journal Article
Source Journal of Neuro-Ophthalmology, December 2021, Volume 41, Issue 4
Collection Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/
Publisher Lippincott, Williams & Wilkins
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management © North American Neuro-Ophthalmology Society
ARK ark:/87278/s6efgtpa
Setname ehsl_novel_jno
ID 2116235
Reference URL https://collections.lib.utah.edu/ark:/87278/s6efgtpa
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