The role of early life socioeconomic status in female breast cancer incidence

Update item information
Publication Type thesis
School or College College of Social & Behavioral Science
Department Geography
Author Butler, Jared Thomas
Title The role of early life socioeconomic status in female breast cancer incidence
Date 2013-12
Description The effect of affluence upon increased breast cancer incidence is a widely studied phenomenon. However, utilizing affluence at time of diagnosis may prove noninformative due to residential mobility and variable socioeconomic status (SES) through an individual's life. Examining a cohort of women born in Utah from 1945-1959, this study seeks to determine whether individual and/or area-based SES at birth is associated with female breast cancer risk in life, and to determine if the incidence of female breast cancer is spatially clustered based on residential location at birth. We utilized Cox proportional hazards (PH) models as a means of determining the impact of SES at birth and adult breast cancer incidence. To examine the potential for spatial clustering patterns at birth, space time scan statistics were run employing 1960 census tracts based on cohort members' residence at birth. Cox PH modeling found that women born into low SES families were less likely to develop breast cancer than women born into the highest SES groups (Q1 HR=0.83 95% CI: 0.72-0.97; Q2 HR=0.81 95% CI: 0.69-0.96). Spatial clustering was limited, though women born in a 2-year time period in South Salt Lake City and the Sugarhouse neighborhood of Salt Lake City exhibited significantly higher risk than their peers (RR=2.2, p-value 0.005). This study seeks to identify mechanisms linking SES at birth to adult breast cancer onset. The findings stress the importance of living and economic conditions at birth and their long-term impacts on breast cancer risk factors and incidence.
Type Text
Publisher University of Utah
Subject Breast cancer; Clustering; Incidence; Life course; Socioeconomic; Utah
Dissertation Institution University of Utah
Dissertation Name Master of Science
Language eng
Rights Management Copyright © Jared Thomas Butler 2013
Format Medium application/pdf
Format Extent 1,989,056 bytes
Identifier etd3/id/2694
ARK ark:/87278/s6pv9tjv
Setname ir_etd
Date Created 2014-02-07
Date Modified 2017-05-31
ID 196269
Reference URL