Exploring risk factors associated with spasmodic dysphonia: an epidemiological approach

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Publication Type thesis
School or College College of Health
Department Communication Sciences & Disorders
Author Kimber, Kamille
Title Exploring risk factors associated with spasmodic dysphonia: an epidemiological approach
Date 2009-06-20
Description Spasmodic dysphonia (SD) is a focal laryngeal dystonia that produces involuntary spasms of the vocal folds, resulting in a strained-strangled voice quality. Currently, there is no cure for SD, and little is known regarding possible risk factors, diseases, and/or exposures that contribute to its development. To shed light on the pathogenesis of SD, the present case-control, epidemiological investigation compared questionnaire responses obtained from individuals with SD (n=\46) and a medical treatment-seeking, control group (/i=105) regarding possible risks, diseases, and exposures. Differences between groups were examined using contingency tables, chi square analyses, odds ratios, and stepwise logistic regression. A stepwise logistic regression analysis identified several factors that were more prevalent in the SD group (p <0.15), including: (1) a personal history of mumps and intense occupational voice use; (2) an immediate family history of essential tremor, cancer, meningitis; and (3) an extended family history of multiple sclerosis, hypertension, and voice disorders. Cumulatively, these factors accounted for nearly 30% of the variance in SD group membership. The results of this case-control investigation suggest likely interactions between genetic factors, disease states and exposures, and voice use demands that contribute to the origins of SD.
Type Text
Publisher University of Utah
Subject Laryngeal dystonia; Voice disorders
Dissertation Institution University of Utah
Dissertation Name MS
Language eng
Relation is Version of Digital reproduction of "Exploring risk factors associated with spasmodic dysphonia: an epidemiological approach" J. Willard Marriott Library Special Collections RF21.5 2009 .K55
Rights Management © Kamille Kimber
Format Medium application/pdf
Format Extent 46,914 bytes
Identifier us-etd2,121741
Source Original: University of Utah J. Willard Marriott Library Special Collections
Conversion Specifications Original scanned on Epson GT-30000 as 400 dpi to pdf using ABBYY FineReader 9.0 Professional Edition.
ARK ark:/87278/s6t447rm
Setname ir_etd
Date Created 2012-04-23
Date Modified 2021-05-06
ID 193494
Reference URL https://collections.lib.utah.edu/ark:/87278/s6t447rm
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