The affects of passaging strains of Mycoplasma arthritidis and Mycoplasma hominis, type 2, in the rat.

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Publication Type thesis
School or College School of Medicine
Department Pathology
Author Rowland, Laura Golightly.
Title The affects of passaging strains of Mycoplasma arthritidis and Mycoplasma hominis, type 2, in the rat.
Date 1969-06
Description Diphosphoglycerate (DPG) plays an integral part in the transport of oxygen to tissues. By binding reversibly with hemoglobin, DPG decreases hemoglobin's affinity for oxygen and increases oxygen availability to the tissues. Multiple factors affect the synthesis and binding ability of DPG and indirectly alter oxygen availability to the tissues. General aesthesia imposes many physiologic alterations which, when considered individually, are known to alter DPG levels. The purpose of the present study was to quantify, describe, and compare the preoperative and postoperative measurements of DPG levels in non-acute patients undergoing anesthesia. DPG levels on 30 healthy adults (19 females and 11 males) were obtained before and after elective surgery under general anesthesia. DPG levels decreased from a preoperative mean of 2.34 um-mols/ml to a postoperative mean of 1.83 um-mols/ml (p<.001). This decrease was unrelated to type of anesthetic agent, length of anesthesia, or estimated blood loss. Although actual decreases in tissues oxygenation postoperatively were not measured, some decrease may occur as a result of the decrease in DPG levels. Therefore, nursing measures which promote optimal tissue oxygenation should be directed toward every postoperative patient.
Type Text
Publisher University of Utah
Subject Llyophilization; Biochemical
Subject MESH Serology; Mycoplasma
Dissertation Institution University of Utah
Dissertation Name MS
Language eng
Relation is Version of Digital reproduction of "The affects of passaging strains of Mycoplasma arthritidis and Mycoplasma hominis, type 2, in the rat." Spencer S. Eccles Health Sciences Library. Print version of "The affects of passaging strains of Mycoplasma arthritidis and Mycoplasma hominis, type 2, in the rat." available at J. Willard Marriott Library Special Collection. QR6.5 1969 .R6.
Rights Management © Laura Gologhtly Rowland.
Format Medium application/pdf
Identifier us-etd2,97
Source Original: University of Utah Spencer S. Eccles Health Sciences Library (no longer available).
Funding/Fellowship Rheumatism and Arthritis grant (#255-517-815) and a PPLO grant (#255-514-002).
ARK ark:/87278/s6xs68vm
Setname ir_etd
Date Created 2012-04-23
Date Modified 2012-04-23
ID 192333
Reference URL https://collections.lib.utah.edu/ark:/87278/s6xs68vm