The relevant anatomy of this disorder involves the inferior olivary nucleus, projecting via the restiform body to the contralateral dentate nucleus, traveling to the contralateral red nucleus via the superior cerebellar peduncle, and finally back to the inferior olivary nucleus via the central tegmental tract. Lesions in the dentate nucleus or central tegmental tract cause pseudohypertrophy of the inferior olive, which is seen in all cases of ocular-palatal myoclonus. A patient with this disorder is shown. The constellation is also called "oculo-palatal tremor."
Robert B. Daroff, MD, Professor of Neurology, School of Medicine, CASE Western Reserve University, University Hospitals - Case Medical Center
Spencer S. Eccles Health Sciences Library, University of Utah