Walsh & Hoyt: Topical Diagnosis of Lesions of the Lateral Geniculate Body

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Identifier wh_ch12_p523
Title Walsh & Hoyt: Topical Diagnosis of Lesions of the Lateral Geniculate Body
Subject Optic Nerve Diseases; Chiasmal Disorders; Retrochiasmal Disorders; Lateral Geniculate Body Lesions, Topical Diagnosis
Creator Leonard A. Levin, MD, PhD. Chair of Ophthalmology, McGill University
Description Lesions affecting the lateral geniculate body (LGB; also lateral geniculate nucleus [LGN]) are less commonly diagnosed than those of the optic tract. At the beginning of the 20th century, it was accepted that incongruity of homonymous field defects is most pronounced with lesions near the junction of the optic chiasm and tract and diminishes progressively with more posterior lesions. This diagnostic perimetric axiom was attributed to a gradual alignment in the optic tract of the crossed and uncrossed visual axons from corresponding retinal areas. However, this theory was challenged by several clinicoanatomic case studies and two clinical reports suggesting that lesions of the lateral geniculate body produce significantly incongruous homonymous field defects. Gunderson and Hoyt subsequently reported quantitative perimetric studies in two patients with lesions of the lateral geniculate body. One patient had a progressive hemianopia that began as an incongruous, relative wedge-shaped homonymous defect and ultimately resulted in a complete homonymous hemianopia with splitting of the macula. At autopsy, the patient had a diffuse pilocytic astrocytoma in the right temporal lobe, thalamus, and brain stem that completely replaced the right LGB. The second patient had a small arteriovenous malformation localized to the LGB. Hoyt later described these two patients and two others in a more extensive discussion of perimetric findings in patients with lesions of the LGB. The most striking perimetric feature in these patients was the extensive incongruity of their visual field defects.
Publisher Spencer S. Eccles Health Sciences Library, University of Utah
Date 2005
Type Text
Format application/pdf
Format Creation application/pdf
Relation is Part of Neuro-Ophthalmology Virtual Education Library (NOVEL): Walsh and Hoyt's Clinical Neuro-Ophthalmology, 6th Edition
Rights Management Copyright 2012. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright
Holding Institution Spencer S. Eccles Health Sciences Library
Collection Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
Language eng
ARK ark:/87278/s6pv9txs
Setname ehsl_novel_novel
ID 186373
Reference URL https://collections.lib.utah.edu/ark:/87278/s6pv9txs
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