Identifier |
20160301_nanos_sciplatform2_02 |
Title |
Neuroprotective Effects of ST266 in Experimental Optic Neuritis (.pdf) |
Creator |
Kenneth S. Shindler; Reas S Khan; Kimberly Dine; Larry Brown |
Affiliation |
(KSS) (RSK) (KD) University of Pennsylvania/Ophthalmology, Philadelphia, PA; (LB) Stemnion, Inc., Pittsburgh, PA |
Subject |
Optic Neuritis; Neuroprotection; Retinal Ganglion Cell; Multiple Sclerosis |
Description |
Optic neuritis, demyelinating optic nerve inflammation, often occurs in multiple sclerosis (MS) patients. Loss of retinal ganglion cells (RGCs) and their axons also occurs in optic neuritis, and correlates with permanent vision loss. ST266 is a novel biologic mixture of growth factors and cytokines secreted from Amnion-derived Multipotent Progenitor (AMP) cells, that exhibits anti-inflammatory and neuroprotective properties in a variety of disease models. The ability of ST266 to suppress optic neuritis in the EAE model of MS was examined. |
Date |
2016-03-01 |
Language |
eng |
Format |
application/pdf |
Type |
Text |
Source |
2016 North American Neuro-Ophthalmology Society Annual Meeting |
Relation is Part of |
NANOS Annual Meeting 2016: Scientific Platform Session II |
Collection |
Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu |
Publisher |
Spencer S. Eccles Health Sciences Library, University of Utah |
Holding Institution |
North American Neuro-Ophthalmology Association. NANOS Executive Office 5841 Cedar Lake Road, Suite 204, Minneapolis, MN 55416 |
ARK |
ark:/87278/s6hb2c4q |
Context URL |
The NANOS Annual Meeting Neuro-Ophthalmology Collection: https://novel.utah.edu/collection/NAM/toc/ |
Setname |
ehsl_novel_nam |
ID |
185327 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6hb2c4q |