Long-Term Evolution Optic Disc Drusen - 57 Year Follow-Up (.pdf)

Optic disc drusen (ODD) are hyaline deposits in the optic nerve head. The pathophysiology remains unknown, but the formation of ODD is probably based on alterations of axoplasmic transport in the optic nerve head. Long-term evolution of ODD anatomy and visual field defects in ODD patients is a key factor for learning more about the pathophysiology and prognosis of the condition. With a mean follow-up period of 57 years, this is the first study that evaluates optic disc anatomy and visual fields in patients with ODD over a life-span.