Identifier |
20160301_nanos_posters_140 |
Title |
A Photothrombotic Model of Optic Neuropathy Using Mesoporphyrin IX: Our Experience with Rats vs. Mice (.pdf) |
Creator |
Peggy Bouzika; Dimosthenis Mantopoulos; Joseph F. Rizzo; Joan W. Miller; Demetrios G. Vavvas; Dean M. Cestari |
Affiliation |
(PB) (DM) (JSR) (DMC) MEEI/ Neuro-ophthalmology, Boston, MA; (PB) (DM) (JWM) (DGV) MEEI/ Retina, Boston, MA |
Subject |
Ischemic Optic Neuropathy; Photodynamic Treatment; Mesoporphyrin IX; Animal Model |
Description |
We recently developed a photothrombotic model of optic neuropathy in rodents using mesoporphyrin IX as the photosensitizer. While originally considering similar laser parameters for both rats and mice, our experiments showed that the optic nerve (ON) response to the photodynamic treatment applied was very different between the two species. We present here some of the challenges faced, especially when trying to set up this model in mice. |
Date |
2016-03-01 |
Language |
eng |
Format |
application/pdf |
Type |
Text |
Source |
2016 North American Neuro-Ophthalmology Society Annual Meeting |
Relation is Part of |
NANOS Annual Meeting 2016: Poster Presentations |
Collection |
Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu |
Publisher |
Spencer S. Eccles Health Sciences Library, University of Utah |
Holding Institution |
North American Neuro-Ophthalmology Association. NANOS Executive Office 5841 Cedar Lake Road, Suite 204, Minneapolis, MN 55416 |
Rights Management |
Copyright 2016. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
ARK |
ark:/87278/s63v2q3v |
Context URL |
The NANOS Annual Meeting Neuro-Ophthalmology Collection: https://novel.utah.edu/collection/NAM/toc/ |
Setname |
ehsl_novel_nam |
ID |
185183 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s63v2q3v |