MALT Lymphoma Masquerading as Thyroid Orbitopathy (.pdf)

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Identifier 20160228_nanos_posters_106
Title MALT Lymphoma Masquerading as Thyroid Orbitopathy (.pdf)
Creator Joseph G. Chacko; Jacob Martin; Rudy L. Van Hemert; Rohan Samant; Giovanni Insuasti-Beltran; Sarkis Nazarian
Affiliation (JGC) (JM) (SN) UAMS / Ophthalmology, Little Rock, AR; (RLV) (RS) UAMS / Radiology, Little Rock, AR; (GI) UAMS / Pathology, Little Rock, AR
Subject Lymphoma; MALT; Orbital Mass
Description 67 y/o WF referred for disc edema OS, complaining of distortion OS x 1 year. No headaches. PMH: hypertension and hypothyroidism. SH: 40 pack-years of smoking. Exam revealed 20/20 and 20/25. Visual fields were FTC, and color vision was normal. Pupils: 1+ reaction OU, and no RAPD. EOM revealed mild limitations. Exam demonstrated RLL and LLL edema, bilateral brow ptosis, bilateral Queen Anne sign, and lid retraction with an MRD of 6 mm OU. Hertel was 20 and 22 with a base of 97. DFE OS revealed 2+ disc edema. TED with compressive optic neuropathy OS was suspected. CT revealed bilateral apical orbital soft tissue masses with widening of the superior orbital fissures bilaterally and extension on the left side into the left pterygopalatine fossa and along branches of the left trigeminal nerve. MRI further characterized the masses limited to the posterior third of the orbits R>L, bilateral infiltration of the adjacent tendons of the EOMs with infiltration into the muscle bellies on the right, and extension along the left petrous ridge and left free edge of the tentorium. Left upper cervical adenopathy was identified by imaging and then biopsied by ENT. Results revealed a low-grade marginal zone lymphoma (MALToma) composed of CD20+ B-cells with abnormal coexpression of BCL2. Concurrent flow cytometry identified a population of CD5-/CD10- kappa light chain restricted B-cell population. CT chest, abdomen, and pelvis was unremarkable.
Date 2016-02-28
Language eng
Format application/pdf
Type Text
Source 2016 North American Neuro-Ophthalmology Society Annual Meeting
Relation is Part of NANOS Annual Meeting 2016: Poster Presentations
Collection Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
Publisher Spencer S. Eccles Health Sciences Library, University of Utah
Holding Institution North American Neuro-Ophthalmology Association. NANOS Executive Office 5841 Cedar Lake Road, Suite 204, Minneapolis, MN 55416
Rights Management Copyright 2016. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright
ARK ark:/87278/s67w9k20
Context URL The NANOS Annual Meeting Neuro-Ophthalmology Collection: https://novel.utah.edu/collection/NAM/toc/
Setname ehsl_novel_nam
ID 185120
Reference URL https://collections.lib.utah.edu/ark:/87278/s67w9k20
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