Lipocalin-2 Expression in Demyelinating Optic Neuritis of Experimental Autoimmune Encephalomyelitis Model and their Pivotal Role

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Identifier 20150223_nanos_sciplatform1_01-1
Title Lipocalin-2 Expression in Demyelinating Optic Neuritis of Experimental Autoimmune Encephalomyelitis Model and their Pivotal Role
Creator Bo Young Chun; Jong-Heon Kim; Youngpyo Nam; Seungwoo Han; Kyoungho Suk
Affiliation (BYC) Department of Ophthalmology, Kyungpook National University Hospital, Daegu, Korea; (JK) (YN) (KS) Department of Pharmacology, Brain science and engineering institute, Kyungpook National University School of Medicine, Daegu, Korea; (SH) Division of Rheumatology, Department of Internal Medicine, Daegu Fatima Hospital, Daegu, Korea
Subject Experimental Autoimmune Optic Neuritis; Lipocalin 2; Demyelination; Reactive Astrocytosis; Microglial Activation
Description The purpose of this study is to determine the role of lipocalin 2 (LCN2) in experimental autoimmune optic neuritis (EAON) model. We compared degrees of neuro-inflammation between LCN2 knock out (KO) mice and wild type (WT) littermates by histological analysis of demyelination, reactive astrocytosis and proliferation of microglia.
Date 2015-02-23
Language eng
Format application/pdf
Format Creation Microsoft PowerPoint
Type Text
Source 2015 North American Neuro-Ophthalmology Society Annual Meeting
Relation is Part of NANOS Annual Meeting 2015 Platform Session 1
Collection Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
Publisher Spencer S. Eccles Health Sciences Library, University of Utah
Holding Institution North American Neuro-Ophthalmology Association. NANOS Executive Office 5841 Cedar Lake Road, Suite 204, Minneapolis, MN 55416
Rights Management Copyright 2013. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright
ARK ark:/87278/s6dz3g7z
Context URL The NANOS Annual Meeting Neuro-Ophthalmology Collection: https://novel.utah.edu/collection/NAM/toc/
Setname ehsl_novel_nam
ID 185049
Reference URL https://collections.lib.utah.edu/ark:/87278/s6dz3g7z
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