Acute Onset Internuclear Ophthlamoplegia And Migraine Headache

Usually a diagnosis of exclusion in adults, ophthalmoplegic migraine is characterized by recurrent attacks of migraine headaches associated with paresis of one or more ocular cranial nerves, in the absence of any demonstrable intracranial lesion other than MRI changes within the affected nerve. Paresis of the cranial nerves third, fourth and sixth were described. Medial longitudinal fasciculus involvement and subsequent internuclear ophthalmoplegia (INO) in association with migraine headache, as well as the INO resolution with migraine abortive therapy is not reported in the literature.