A Novel Diagnostic Tool for Myasthenia Gravis: Ocular Vestibular Evoked Myogenic Potentials (oVEMP)

Introduction: Diagnosis of myasthenia gravis (MG) can be challenging, especially in patients with isolated ocular involvement, negative autoantibodies and absence of the characteristic decrement in repetitive nerve stimulation. Ocular vestibular evoked myogenic potentials (oVEMP) are a recently developed, non-invasive test that allows electromyographic registration of extraocular muscle activity. Originally, the test was designed to assess vestibular function. We adapted oVEMP to detect the decrement in extraocular muscles of MG patients.