Identifier |
20150222_nanos_posters_236 |
Title |
Autologous Hematopoietic Stem Cell Transplantation in Neuromyelitis Optica |
Creator |
Fiona Costello, Jodie Burton, Luanne Metz, Peter Duggan, Jan Storek |
Subject |
Neuromyelitis Optica, Optic Neuritis, Autologous Hematopoietic Stem Cell Transplantation, Clinical Recovery |
Description |
"Neuromyelitis Optica (NMO) is an immune-mediated astrocytopathy characterized by frequent demyelinating/necrotizing attacks of optic nerves and spinal cord. Treatments are highly toxic and incompletely effective. Fifty percent of patients are blind in one eye or require a mobility aide within 5 years. The immunological features of NMO, coupled with its severity make it an ideal candidate for a trial of autologous non-ablative hematopoietic stem cell transplantation (AHSCT) with the goal of disease remission and freedom from immunosuppressive medications. The objective of this study is to determine if NMO patients, despite maintenance therapy, experience a reduction in relapses and disability without ongoing immunosuppressants after AHSCT. We hypothesize a greater than or equal to 50% reduction in the proportion of patients relapsing 3 years post-transplant." |
Date |
2015-02-22 |
Language |
eng |
Format |
application/pdf |
Format Creation |
application/pdf |
Type |
Text |
Source |
2015 North American Neuro-Ophthalmology Society Annual Meeting |
Relation is Part of |
NANOS 2015: Poster Presentations |
Collection |
Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu |
Publisher |
Spencer S. Eccles Health Sciences Library, University of Utah |
Holding Institution |
North American Neuro-Ophthalmology Association. NANOS Executive Office 5841 Cedar Lake Road, Suite 204, Minneapolis, MN 55416 |
Rights Management |
Copyright 2013. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
ARK |
ark:/87278/s65q82x8 |
Context URL |
The NANOS Annual Meeting Neuro-Ophthalmology Collection: https://novel.utah.edu/collection/NAM/toc/ |
Contributor Primary |
Fiona Costello |
Contributor Secondary |
Jodie Burton, Luanne Metz, Peter Duggan, Jan Storek |
Setname |
ehsl_novel_nam |
ID |
184602 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s65q82x8 |