Robust Optic Nerve Head Analysis Based On 3D Optical Coherence Tomography

Many conditions such as glaucoma (GD), optic neuritis (ON), multiple sclerosis (MS) or idiopathic intracranial hypertension (IIH) affect the optic nerve head (ONH). Optical coherence tomography (OCT) allows 3D ONH imaging. However, current ONH analysis methods work in only atrophic or in swollen ONH but not both. Manual steps for masking Bruch's membrane opening (BMO) or ONH center are regularly required. Our objective was to develop a robust and fully automatic ONH quantification algorithm applicable in atrophic, normal and swollen conditions.