Subretinal Choroidal Neovascularization Associated with Unilateral Papilledema and IIH

"Choroidal Neovascularization (CNV) secondary to Idiopathic Intracranial Hypertension (IIH) is rare. CNV produces visual obscurations, decreased visual acuity(VA), and permanent retinal damage if the CNV moves toward and into the fovea. The biomechanics of the inception of CNV with IIH are not fully understood, hypothetically pressure exerted by a swollen optic disk may create a discontinuity in the Bruch's Membrane resulting in growth of vessels under the RPE and sensory retina. Hypoxia due to axonal swelling may create necessary conditions for angiogenesis and vasculogenesis via expression of VEGF, HSCs, and other angiogenic cytokines in subretinal space. CNV associated with IIH may successfully regress following intervention, but there is no consensus on a treatment choice."