Treatment of Retinal Disorders

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Identifier 20130211_nanos_journalclubsympos_01-2
Title Treatment of Retinal Disorders
Creator Jirawuthiworavong, Guy
Subject Central Retinal Vein Occlusion; Macular Edema; Intravitreal Injection; Anti-Vascular Endothelial Growth Factor (Anti-VEGF); Dexamethasone Intravitreal Implant
Description Approximately 0.1% to 0.5% of patients of middle age and older will suffer from a central retinal vein occlusion. Vision loss can be devastating rendering patients to be legally blind in the affected eye. The Central Vein Occlusion Study published in 1997 showed that patients presenting with less than 20/200 vision only had a 20% chance of improving their vision.4 Approximately 31% of patients with less than 20/200 vision developed iris and angle neovascularization. Loss of vision can be due to nonperfusion/ retinal ischemia with resultant macular edema. Clinical trials in the management of central retinal vein occlusions over the last three years have revolutionized how retina specialists treat macular edema. Goals are to reduce capillary permeability and inhibit expression of VEGF genes and their metabolic pathways.5 As a result, multiple options exist now as part of the armamentarium. Unfortunately, many of these new treatments (intravitreal triamcinolone acetonide, intravitreal anti-vascular endothelial g w factor (anti-VEGF) agents, sustained release dexamethasone intravitreal implant) require repeated treatments. Patients have benefited from the newer modalities by improving chances of gaining functional vision after experiencing a devastating visually compromising disease.
Relation is Part of NANOS 2013: Jorunal Club
Contributor Primary Bhatti, MT
Contributor Secondary Prasad, Sashank
Publisher Spencer S. Eccles Health Sciences Library, University of Utah
Date 2013-02-11
Type Image/MovingImage
Format video/mp4
Format Creation application/video
Source 2013 North American Neuro-Ophthalmology Society Annual Meeting
Rights Management Copyright 2013. For further information regarding the rights to this collection, please visit:
Holding Institution North American Neuro-Ophthalmology Association. NANOS Executive Office 5841 Cedar Lake Road, Suite 204, Minneapolis, MN 55416
Collection Neuro-ophthalmology Virtual Education Library: NOVEL
Language eng
ARK ark:/87278/s6vb1fvp
Setname ehsl_novel_nam
Date Created 2015-02-02
Date Modified 2017-04-19
ID 184411
Reference URL