The Injury Response Factor JUN is Expressed in Multiple Retinal Cell Types After Excitotoxic Insult

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Identifier 20140304_nanos_posters_049
Title The Injury Response Factor JUN is Expressed in Multiple Retinal Cell Types After Excitotoxic Insult
Creator Juan Ayala-Haedo; Kimberly Fernandes; Rebecca Rausch; Berkeley Farenthold; Richard Libby
Affiliation (JA) Flaum Eye Institute University of Rochester, Rochester , NY
Subject Excitotoxicity; Retinal Ganglion Cell; Muller Glial Cells
Description Excitotoxicity has been suggested to contribute to retinal ganglion cell (RGC) death in many diseases. The transcription JUN plays a major role in regulating RGC death after a variety of insults and has been shown to control excitotoxic neuronal death in other systems. Also, a recent study suggested that TNF released from Muller glial cells mediates excitotoxicity induced RGC death. Interestingly, JUN can control injury induced TNF expression. Therefore, JUN may play a central role in excitotoxicity induced RGC death.
Date 2014-03-04
Language eng
Format application/pdf
Type Text
Source 2014 North American Neuro-Ophthalmology Society Annual Meeting
Relation is Part of NANOS 2014: Poster Presentations
Collection Neuro-Ophthalmology Virtual Education Library: NANOS Annual Meeting Collection: https://novel.utah.edu/collection/nanos-annual-meeting-collection/
Publisher North American Neuro-Ophthalmology Society
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management Copyright 2013. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright
ARK ark:/87278/s6z92k6s
Setname ehsl_novel_nam
ID 184178
Reference URL https://collections.lib.utah.edu/ark:/87278/s6z92k6s
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