| Identifier |
20130212_nanos_sciplatform2_06 |
| Title |
SIRT1 Reduces Oxidative Stress and Delays RGC Loss Following Optic Nerve Crush |
| Creator |
Kenneth S. Shindler; Ling Zuo; Reas S. Khan; Kimberly Dine; Wen Wu |
| Affiliation |
(KSS) (RSK) (KD) (WW) University of Pennsylvania/Ophthalmology, Philadelphia, PA; (LZ) Second Hospital of Jilin University/Ophthalmology, Jilin, China |
| Subject |
Neuroprotection; Resveratrol; Oxidative Stress; Retinal Ganglion Cells; Traumatic Optic Neuropathy |
| Description |
SIRT1 activation prevents loss of retinal ganglion cells (RGCs) in experimental optic neuritis. While the mechanism of this effect is unknown, a role in reduction of oxidative stress has been suggested. Because oxidative stress is a common mechanism of neuronal damage, we hypothesized that SIRT1 may reduce RGC loss due to oxidative stress following traumatic injury. |
| Date |
2013-02-12 |
| Language |
eng |
| Format |
application/pdf |
| Type |
Text |
| Source |
2013 North American Neuro-Ophthalmology Society Annual Meeting |
| Relation is Part of |
NANOS 2013: Platform Presentations (Session II) |
| Collection |
Neuro-Ophthalmology Virtual Education Library: NANOS Annual Meeting Collection: https://novel.utah.edu/collection/nanos-annual-meeting-collection/ |
| Publisher |
North American Neuro-Ophthalmology Society |
| Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management |
Copyright 2013. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
| ARK |
ark:/87278/s6351s2z |
| Setname |
ehsl_novel_nam |
| ID |
183372 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6351s2z |
