Invasive Thymoma Presenting with Ocular Myasthenia Gravis

Invasive thymoma is an uncommon neoplasm with an aggressive course that has been noted with increasing frequency in recent years. Forty percent of invasive thymomas are associated with paraneoplastic syndromes including myasthenia gravis. We report two patients with ocular MG with biopsy confirmed invasive thymoma. Prompt computed tomography (CT) of the chest should be performed in all patients with MG including ocular MG. To our knowledge this is the largest series in the English language ophthalmic literature of invasive thymoma with ocular MG.