Comparison of RNFL Measurements and Visual Function Among Patients with MS

Optical coherence tomography (OCT) measured RNFL values are reduced among MS patients and correlate with diminished visual performance. We aim to compare RNFL values among patients with progressive MS, relapsing remitting MS, optic neuritis (ON) as a clinically isolated syndrome (CIS), recurrent ON and normal control subjects. We also aim to compare tests of visual function with RNFL measurements among MS and ON patients to determine whether axon loss in the afferent visual pathway is the substrate for persistent visual impairment.