Behavioural and Cortical Activation Patterns Following Optic Neuritis

Optic neuritis (ON) is a common condition chat causes reversible loss of vision in young patients, following an idiopathic inflammatory demyelination. There is an ongoing debate about whether ON's clinical aspects derives from parvocellular or magnocellular deficit. Visual function improvement is common in this disease, and is usually attributed to peripheral recovery (i.e. remydination). Our previous study has suggested chat central reorganization processes in me lateral occipital complex (LOC), may also be involved in recovery. The aim of this work is to study longitudinally the behavioural and cortical changes following an acme ON episode, in different visual casks.