Clonally-Expanded Plasma Cells in Neuromyelitis Optica Cerebrospinal Fluid Produce IgG Against Aquaporin-4

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Identifier 20090224_nanos_sciplatform_08.pdf
Title Clonally-Expanded Plasma Cells in Neuromyelitis Optica Cerebrospinal Fluid Produce IgG Against Aquaporin-4
Creator Bennett, Jeffrey; Lam, Chiwah; Bautista, Katherine; DuPree, Cecily; Glogowska, Magdalena; Case, David; Saikali, Philippe; Antel, Jack; Reddy, Sudhakar; Hemmer, Bernhard; Owens, Gregory; Gilden, Donald
Subject neuromyelitis optica; aquaporin-4; plasma cells; optic neuritis
Description Neuromyelitis optica immunoglobulin G (NMO-IgG) binds the aquaporin-4 (AQP-4) water channel of astrocytes that are abundant in the perivessel and subpial areas of the brain. NMO-IgG appears specific for NMO and is now included as a diagnostic criterion for disease.
Date 2009-02-24
Language eng
Format application/pdf
Format Creation application/pdf
Type Text
Source 2009 North American Neuro-Ophthalmology Society Annual Meeting
Relation is Part of NANOS 2009: Scientific Platform Presentations (Session II)
Collection Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
Publisher Spencer S. Eccles Health Sciences Library, University of Utah
Holding Institution North American Neuro-Ophthalmology Association. NANOS Executive Office 5841 Cedar Lake Road, Suite 204, Minneapolis, MN 55416
Rights Management Copyright 2010. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright
ARK ark:/87278/s66d90cv
Context URL The NANOS Annual Meeting Neuro-Ophthalmology Collection: https://novel.utah.edu/collection/NAM/toc/
Contributor Secondary Alfredo Sadun, MD, PhD; Fiona Costello, MD, FRCP
Setname ehsl_novel_nam
ID 180546
Reference URL https://collections.lib.utah.edu/ark:/87278/s66d90cv
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