Identifier |
20090224_nanos_posters_095.pdf |
Title |
Elevated Serum Hepcidin and Increased Hepcidin Synthesis in Biopsy Specimens in Patients with Giant Cell Arteritis |
Creator |
Bradley Katz; Ivana De Domenico; Curry Koening; Kathleen Digre; Judith Warner; Jerry Kaplan |
Affiliation |
University of Utah, Salt Lake City, UT |
Subject |
Giant Cell Arteritis; Temporal Arteritis; Hepcidin; RT-PCR; Lipopolysaccharide |
Description |
Hepcidin is a 25amino acid disulfide-rich peptide that acts as a systemic iron-regulatory hormone. Hepcidin synthesis increases during inflammation, trapping iron in macrophages and decreasing plasma iron concentrations. Increased hepcidin synthesis underlies the phenomenon of the anemia of chronic disease. Hepcidin was recently thought to be produced exclusively in the liver, but has recently been shown to be synthesized in Mller cells, where hepcidin appears to regulate retinal iron levels. |
Date |
2009-02-24 |
Language |
eng |
Format |
application/pdf |
Type |
Text |
Source |
2009 North American Neuro-Ophthalmology Society Annual Meeting |
Relation is Part of |
NANOS 2009: Poster Presentations |
Collection |
Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu |
Publisher |
Spencer S. Eccles Health Sciences Library, University of Utah |
Holding Institution |
North American Neuro-Ophthalmology Association. NANOS Executive Office 5841 Cedar Lake Road, Suite 204, Minneapolis, MN 55416 |
Rights Management |
Copyright 2010. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
ARK |
ark:/87278/s612900x |
Context URL |
The NANOS Annual Meeting Neuro-Ophthalmology Collection: https://novel.utah.edu/collection/NAM/toc/ |
Setname |
ehsl_novel_nam |
ID |
180501 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s612900x |